Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. McAusland  S, Walters ABCD consortium investigators designed and implemented the study and/or provided data but did not necessarily participate in analysis or writing of this report. Results  This was accompanied by a structured interview for prodromal syndromes (SIPS). Persisting psychotic-like experiences are associated with both externalising and internalising psychopathology in a longitudinal general population child cohort.  AE, Barragan Small but significant associations were found between higher PQ-BC scores and greater scores on each of the child-rated internalizing symptom modules for Total (β range, 0.218 [95% CI, 0.189-0.246] to 0.273 [95% CI, 0.245-0.301]) and Distress (β range, 0.248 [95% CI, 0.220-0.277] to 0.310 [95% CI, 0.281-0.338]) scores as well as with bipolar symptoms (Total score: β = 0.200 [95% CI, 0.171-0.230]; Distress score: β = 0.197 [95% CI, 0.168-0.226]). Weintraub  KS, Furthermore, the choice to read questions to participants to ensure comprehension may have influenced disclosure willingness for some individuals.  MJ, van den Bree Data for this study were collected from June 1, 2016, through August 31, 2017.  L, Cadenhead  et al.  S, Kelly Screen given as part of standard care. A socio-demographic questionnaire, the Prodromal Questionnaire-Brief Version (PQ-B) and the Strengths and Difficulties Questionnaire (SDQ) were administered to each student.  F, Faraone Mean Total and Distress Prodromal Questionnaire–Brief Child Version (PQ-BC) Scores for Family History of Psychosis, Depression, and Mania, Table 1.  JT, a.  et al. Lancefield OBJECTIVE To examine the construct validity and psychometric properties of a measure of PLEs, the Prodromal Questionnaire-Brief Child Version (PQ-BC). The speech delays composite was coded as the summation of a delay in speaking a first word and parent-rated concern regarding speech development (eMethods in the Supplement).  S, Dikmen  NG. Welham  K, Banerjea Laurens  R, Childhood psychoticlike experiences (PLEs) are associated with greater odds of a diagnosis of a psychotic disorder during adulthood. However, these weak associations are consistent with previous research examining parent-rated PLEs,39 indicating potential differences between children and parents in the interpretation of PLEs or a lack of reporting these experiences to parents. Anxiety and depression symptoms in psychometrically identified schizotypy. Change in fit from the metric to scalar invariance model also passed invariance criteria for both PQ-BC scores, suggesting similar mean PQ-BC response profiles across groups. Critical revision of the manuscript for important intellectual content: Karcher, Barch, Avenevoli, Savill, Huber, Simon, Sher, Loewy.  et al. The results are compatible with findings that working memory impairments are associated with psychosis risk and early psychotic symptoms in adolescence.34,36,67 Consistent with previous research,34 the results showed some support for deficits in reading and processing speed being related to psychosis risk. We assessed a consecutive patient sample of 3533 young adults who were help-seeking for nonpsychotic disorders at the secondary mental health services in The Hague with the PQ.  R. Is earlier intervention for schizophrenia possible? 2013. Model Estimates for Demographic Covariates for Neuropsychological Test Performance, eTable 6.  S, Blailes Measurement invariance of the Prodromal Questionnaire–Brief among white, Asian, Hispanic, and multiracial populations  [published online January 1, 2017].  DM, Muriungi Fit Statistics for Measurement Invariance Models Across Sex, eTable 4. Biol Psychiatry Cogn Neurosci Neuroimaging. The Prodromal Questionnaire, Brief Version (PQ-B). Barch 2018 08 01; 75(8):853-861.  S, Dikmen  MD, Avenevoli The Total score is the sum of endorsed questions (0 indicates no; 1, yes; possible scores range from 0 to 21). A prospective study of childhood neurocognitive functioning in schizophrenic patients and their siblings. PSQ - Psychosis Screening Questionnaire | AcronymFinder. J Abnorm Psychol. Psychotic-like experiences in a community sample of 8000 children aged 9 to 11 years: an item response theory analysis.  P, Abbott None of these contributors were compensated for this work.  AR, Buckby These results provide support for the construct validity and demonstrate adequate psychometric properties of a self-report instrument designed to measure childhood PLEs, providing evidence that the PQ-BC may be a useful measure of early risk for psychotic disorders.  J. Replication of Associations With Psychotic-Like Experiences in Middle Childhood From the Adolescent Brain Cognitive Development (ABCD) Study. Laurens  J, Reichenberg The Prodromal Questionnaire-Brief version (PQ-B) contains 21 items derived from the PQ. APS and BLIPS). A cut-off of ≥ 6 on the PQ-B total dis-tress score predicted SIPS-UHR/psychosis diagnosis Assessing self-reported clinical high risk symptoms: The psychometric properties of the polish version of the prodromal questionnaire-brief and a proposal for an alternative approach to scoring. The study analyses included 3984 participants (1885 girls [47.3%] and 2099 boys [52.7%]; mean [SE] age, 10.0 [0.01] years). The current results replicate previous research showing that a history of psychotic disorder in first-degree relatives is associated with greater PLEs.26 Of importance, this finding was specific to family history of psychosis and not family history of depression or mania.  D, Kessler  R,  H.  Children’s self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study.  DM. Please enable it to take advantage of the complete set of features! Mayo  et al. Hothorn To examine measurement invariance, stepwise tests of invariance were conducted, first examining potential differences across the 4 racial/ethnic groups and then comparing boys and girls.56 We examined stepwise changes in fit (ie, χ2 test, comparative fit index, and root mean square error of approximation) of 4 progressively restrictive nested models (model details are given in eMethods in the Supplement and the notes in Table 1). The Child Behavior Checklist was used to assess internalizing and externalizing problems as well as attention, thought, and social problems in children as reported by the parent or caregiver. Erlenmeyer-Kimling The Prodromal Questionnaire–Brief Child Version may be a useful measure of early risk for psychotic disorders and is associated with several familial, cognitive, and emotional factors related to psychotic symptoms in older populations.  JP, Reich  R, Harrington  JM, Laurens However, no known, well-validated self-report tools have been designed to measure childhood PLEs.  WS, Kerns Table 1 displays the results of the stepwise invariance tests comparing the race/ethnicity groups for the PQ-BC Total and Distress scores. The Prodromal Questionnaire–Brief Child Version may be a useful measure of early risk for psychotic disorders and is associated with several familial, cognitive, and emotional factors related to psychotic symptoms in older populations.  SA, Murray  T, Murase P values are corrected for false discovery rate. Psychotic-like experiences and depressive symptoms in a community sample of adolescents. This tool is not diagnostic; rather, it is meant to identify young people in need of further assessment for a psychosis risk syndrome as assessed by established clinical interview.  TV,  LH, Albaugh Demographic, physical and mental health assessments in the adolescent brain and cognitive development study: rationale and description.  T, Bretz Psychosis-like experiences and distress among adolescents using mental health services.  S, Bearden  C, Sheffield However, no known, well-validated self-report tools have been designed to measure childhood PLEs. Original and Modified Versions of Questions and Prevalence of Endorsement, eTable 3.  S. Fitting linear mixed-effects models using lme4. Error bars reflect SEs.  et al.  et al.  M, Bolker I feel uninterested in the things I used to enjoy.  AE.  MC, Devlin This finding is in line with extant research showing elevated rates of PLEs in nonwhite participants,15,16 perhaps indicating that factors related to greater PLEs in nonwhite participants in adulthood (ie, discrimination, lower income to needs) (eResults in the Supplement)19,20,60 may already be exerting an influence on PLEs in childhood. To examine the construct validity and psychometric properties of a measure of PLEs, the Prodromal Questionnaire-Brief Child Version (PQ-BC). [Epub ahead of print] PMID: 32105123 . 2020 Sep 6. doi: 10.1111/eip.13035.  KR, Hobbs Ducharme Get the latest research from NIH: https://www.nih.gov/coronavirus. The fluid composite consists of Flanker Inhibitory Control and Attention, List Sorting Working Memory, Dimensional Change Card Sort, Pattern Comparison Processing Speed, and Picture Sequence Memory.  KR, Navarro They rely heavily on the criteria that have been found to identify individuals at ultra high-risk (UHR…  TV, Ducharme National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error.  DC, Krieg JAMA Psychiatry. Higher PQ-BC scores were associated with higher rates of child-rated internalizing symptoms (Total score: β range, 0.218 [95% CI, 0.189-0.246] to 0.273 [95% CI, 0.245-0.301]; Distress score: β range, 0.248 [95% CI, 0.220-0.277] to 0.310 [95% CI, 0.281-0.338]), neuropsychological test performance deficits such as working memory (Total score: β = −0.042 [95% CI, −0.077 to −0.008]; Distress score: β = −0.051 [95% CI, −0.086 to −0.017]), and motor and speech developmental milestone delays (Total score: β = 0.057 [95% CI, 0.026-0.086] for motor; β = 0.042 [95% CI, 0.010-0.073] for speech; Distress score: β = 0.048 [95% CI, 0.017-0.079] for motor; β = 0.049 [95% CI, 0.018-0.081] for speech).  J, Hofstra Kline Participants completed the PQ-BC,14 a 21-item self-report questionnaire, modified for use with children aged 9 to 10 years based on a series of interviews assessing children’s understanding of the items (eMethods and eTable 2 in the Supplement), with a visual response scale included as a Distress scale (eFigure in the Supplement).41 Consistent with previous research,14,17 Total and Distress scores were calculated. Figure..  N, Wigman Rate of completed Prodromal Questionnaire - Brief Version (PQ-B) of incoming patients in clinics. Main outcomes and measures:  L.  A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness-persistence-impairment model of psychotic disorder. Administrative, technical, or material support: Savill, Huber, Simon, Sher. Posted in: Open Access Journal Articles on 06/11/2018 | Link to this post on IFP | Share. Evidence that onset of clinical psychosis is an outcome of progressively more persistent subclinical psychotic experiences: an 8-year cohort study.  et al.  S, Taylor Disclaimer: This report reflects the views of the authors and may not reflect the opinions or views of the NIH or the ABCD consortium investigators. In 2011, Lowey et al. Niarchou  S, Costello National Comorbidity Survey Replication Adolescent Supplement (NCS-A), II: overview and design. Epub 2020 Jun 12. U24 DA041147/DA/NIDA NIH HHS/United States, U01 DA041120/DA/NIDA NIH HHS/United States, T32 MH018261/MH/NIMH NIH HHS/United States, R01 MH107108/MH/NIMH NIH HHS/United States, K05 AA017242/AA/NIAAA NIH HHS/United States, U01 DA041174/DA/NIDA NIH HHS/United States, U01 DA041048/DA/NIDA NIH HHS/United States, U01 DA041156/DA/NIDA NIH HHS/United States, U01 DA041093/DA/NIDA NIH HHS/United States, U54 HD079125/HD/NICHD NIH HHS/United States, U01 DA041134/DA/NIDA NIH HHS/United States, U01 DA041106/DA/NIDA NIH HHS/United States, U01 DA041022/DA/NIDA NIH HHS/United States, R01 HD042974/HD/NICHD NIH HHS/United States, U01 DA041025/DA/NIDA NIH HHS/United States, U01 DA041148/DA/NIDA NIH HHS/United States, U01 DA041089/DA/NIDA NIH HHS/United States, U24 DA041123/DA/NIDA NIH HHS/United States, T32 MH014677/MH/NIMH NIH HHS/United States, U01 DA041028/DA/NIDA NIH HHS/United States, U01 DA041117/DA/NIDA NIH HHS/United States, eScholarship, California Digital Library, University of California. Kline E, Thompson E, Bussell K, Pitts SC, Reeves G, Schiffman J. Schizophr Res. However, no known, well-validated self-report tools have been designed to measure childhood PLEs. Corresponding Author: Nicole R. Karcher, PhD, Department of Psychiatry, Washington University School of Medicine in St Louis, One Brookings Drive, Campus Box 1125, St Louis, MO 63130 (nkarcher@wustl.edu).  S.  Psychotic-like experiences and other antecedents of schizophrenia in children aged 9-12 years: a comparison of ethnic and migrant groups in the United Kingdom. Epub 2014 Jan 8.  TM, Martin  M, van Domburgh Lynam  M, Lieb The results demonstrated measurement invariance across race/ethnicity and sex.  E, Schiffman All Rights Reserved.  JG, Piasecki A screening questionnaire for the detection of serious mental illness in ... General Health prodromal questionnaire-brief version (pq-b), magistrates' courts. To examine the construct validity and psychometric properties of a measure of PLEs, the Prodromal Questionnaire–Brief Child Version (PQ-BC). Lower performance on the Pattern Comparison Processing Speed and Oral Reading Recognition was also associated with higher Total scores (β =  −0.041 [95% CI, −0.074 to −0.008] and β = −0.043 [95% CI, −0.080 to −0.007], respectively) (see eResults in the Supplement).  F, Westfall Calkins We next examined whether race/ethnicity or sex showed mean level differences on PQ-BC scores (Table 2). The change in fit from the configural to the metric invariance model passed invariance criteria for both PQ-BC scores, suggesting that the associations between PQ-BC scale items and the latent variable were similar across groups. A family history of psychotic disorder was associated with higher mean (SE) PQ-BC Total (3.883 [0.352]; β = 0.061; 95% CI, 0.027-0.094) and Distress (10.210 [1.043]; β = 0.051; 95% CI, 0.018-0.084) scores, whereas a family history of depression or mania was not.  S, Burdeus  S, Nazroo Gin Early Interv Psychiatry. Clipboard, Search History, and several other advanced features are temporarily unavailable. Girls had lower PQ-BC Total scores (2.400 [0.215] vs 2.727 [0.214]; β = −0.092; 95% CI, −0.152 to −0.032), but there was no significant association of sex with PQ-BC Distress scores. Data for this study were collected from June 1, 2016, through August 31, 2017. Schiffman  M, Ord  RM, Rutter (Serhii Bobyk/123rf) A wide range of tests were used to gather the data for the study, including the Prodromal Questionnaire-Brief Children Version, which assess child-reported PLEs, The Child Behavior Checklist, The National Institute of Health ToolBox Cognitions Battery-Total Cognitive Composite, and The Sleep Disturbance Scale for Children.  M.  Neurocognitive performance of a community-based sample of young people at putative ultra high risk for psychosis: support for the processing speed hypothesis. During the past several decades, research on psychotic disorders has increasingly focused on early identification of individuals potentially at risk.1,2 The prevalence of psychoticlike experiences (PLEs)3 or subclinical psychotic symptoms (eg, perceptual abnormalities, mild delusional thoughts) is estimated to be approximately 6% to 10% in the general population.4,5 However, the prevalence of PLEs during childhood is estimated to be 13% to 17%,6-8 with some estimates ranging as high as 66% to 68%.9,10 Childhood PLEs are associated with greater odds of developing a psychotic disorder during adulthood,7,11 particularly if PLEs persist over time.12 However, no well-validated self-report tools are available for measuring PLEs and related distress in children as young as 9 years (eg, the Adolescent Psychotic Symptom Screener is validated for use with adolescents aged 11-13 years).13 One self-report tool to identify PLEs, validated in adolescents and adults, is the Prodromal Questionnaire–Brief Version.14 The present study is the first, to our knowledge, to examine the validity of this questionnaire modified for use in a childhood population.  MC, Murphy ent of a child with schizophrenia, posed the question of whether her daughter has schizophrenia. van Os The present study also examined the construct validity of the Prodromal Questionnaire–Brief Child Version (PQ-BC). Kaufman Evidence for early-childhood, pan-developmental impairment specific to schizophreniform disorder: results from a longitudinal birth cohort. However, no known, well-validated self-report tools have been designed to measure childhood PLEs.  Q, Greenspoon Adverse childhood experiences and psychotic-like experiences are associated above and beyond shared correlates: Findings from the adolescent brain cognitive development study.  et al.  WS,  GC, Harms  et al. Polanczyk Last, change in fit from the scalar to strict model also passed invariance criteria for both PQ-BC scores, suggesting that PQ-BC scores measure the same construct across groups.  G, Cognition assessment using the NIH Toolbox. The Palau Early Psychosis Study: neurocognitive functioning in high-risk adolescents. van Os  M, Arango In a recent validation study of a cohort of children aged 9 to 10 years, the Prodromal Questionnaire-Brief Child Version (PQ-BC) demonstrated adequate internal reliability and measurement invariance across race/ethnicity and sex when used as a measure of psychotic-like experiences in childhood.